Lossless whenever available (not necessarily FLAC).
But when it's not, 320 is acceptable, most of the times.
If I can't make the furniture tremble without clipping I'm not satisfied lol.
This thread reminds me that I have to get a new pair of pads and a cable for my HD-25s
I can't tell the difference between lossless and uncompressed, but between lossy and lossless most of the times it's notorious.
For professional or more serious purposes most people use uncompressed formats like WAV or AIF which are kind of pointless for me because they take too much space and are hard to find.